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Described first 180 years ago in 1817 by Dr. James Parkinson, a London physician, it has the attention of researchers around the world, but the cause of this neurological disease remains elusive. Parkinson's disease may produce a great variety of symptoms, but the four basic, so called 'cardinal signs' include tremor, slowness of movement, stiffness of movement, and impairment of balance. There is no test for Parkinson's disease; the diagnosis is established by listening to the symptoms and physical examination by an experienced clinician. As of yet there is no cure, but there are numerous therapies that help the symptoms.
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